Fluorescent micrograph of a Xenopus melanophore, showing microtubules (green), microtubule plus ends (red) and nucleus (blue). Honorable Mention, 2011 Olympus BioScapes Digital Imaging Competition®...

TIRF time-lapse imaging of EB1-GFP (green) and mCherry-tubulin (red). EB1-GFP is seen on microtubule tips that grow to the cortex but does not accumulate on stable microtubule bundles at the equator, ...

How the cell cytoplasm is spatially organized is of fundamental interest. In ordinary animal cells the cytoplasm is organized by a radial array of microtubules, called an aster. Aster microtubules are...

Microtubule fragments exhibiting net treadmilling in a Rac1(Q61L)-expressing PtK1 cell. Microtubule plus ends undergo dynamic instability while their minus ends depolymerize, resulting in net treadmil...

Human foreskin fibroblasts (HFF1) cells transfected with mKusabira-Orange EB3, a marker for growing microtubule ends. Note the dramatic movement of the bright fluorescent markers toward the cell peri...

How the cell cytoplasm is spatially organized is of fundamental interest. In ordinary animal cells the cytoplasm is organized by a radial array of microtubules, called an aster. Aster microtubules are...

TIP activity of CLIP-170(H2)–GFP (a carboxyl truncation of the plus end microtubule tracking protein CLIP-170) in the presence of EB1 protein (a plus end microtubule tracking protein). The movie sho...

Microtubules in a Rac1(Q61L)-expressing PtK1 cell injected with Pak inhibitory fragment PBD/ID(H83L). Microtubules do not exhibit retrograde flow and undergo very little net growth. Epifluorescence i...

GMPCPP abolishes TIP activity of the CLIP-170(H2)–EB1 complex. The movie shows the localization of CLIP-170(H2)–GFP molecules (a carboxyl truncation of the plus end microtubule tracking protein CL...

A normal X. laevis blastomere expressing three tandem GFPs fused to the ensconsin microtubule-binding domain (EMTB-3G; Faire et al., 1999). Single microtubules extend to the cortex, even in these larg...